Dottorato
di ricerca in Biologia Cellulare e Molecolare
Informazioni generali
|
Denominazione del corso |
Biologia Cellulare e Molecolare |
|
Durata prevista |
3 ANNI |
|
Dipartimento |
Dip. BIOLOGIA |
|
Settori scientifico disciplinari
interessati |
Aree interessate |
|
BIO/04 - FISIOLOGIA VEGETALE |
05 - Scienze biologiche |
|
BIO/06 - ANATOMIA COMPARATA E
CITOLOGIA |
05 - Scienze biologiche |
|
BIO/09 - FISIOLOGIA |
05 - Scienze biologiche |
|
BIO/10 - BIOCHIMICA |
05 - Scienze biologiche |
|
BIO/11 - BIOLOGIA MOLECOLARE |
05 - Scienze biologiche |
|
BIO/18 - GENETICA |
05 - Scienze biologiche |
|
BIO/01 - BOTANICA GENERALE |
05 - Scienze biologiche |
|
MED/07 - MICROBIOLOGIA E
MICROBIOLOGIA CLINICA |
06 - Scienze mediche |
|
BIO/13 - BIOLOGIA APPLICATA |
05 - Scienze biologiche |
|
Ateneo |
Dipartimento/Facoltà |
Sede dell'attività didattica |
|
Denominazione |
Stato |
Tipologia di Dottorato |
Sede dell'attività didattica |
|
Université
Paul Sabatier " 118 route de Narbonne, 31062 Toulouse |
FRANCE |
Con tesi in cotutela |
NO |
|
Fondation
Recherche sur le Cancer et les Maladies du Sang Laboratoire de Biologie
Moleculaireet Cellulaire du Cancer (LBMCC) |
LUXEMBOURG |
Con tesi in cotutela |
NO |
Convenzione con soggetti (enti/organizzazioni/istituzioni)
|
n. |
Tipologia del soggetto |
Denominazione del soggetto |
Denominazione nuovo soggetto |
|
1. |
Fondazione |
Telethon |
|
|
2. |
Altro privato |
IRBM |
|
|
3. |
Altro privato |
AIRC |
|
Il principale obbiettivo formativo
del nostro dottorato consiste nella preparazione di ricercatori che siano in
grado di sfruttare le moderne Biotecnologie per affrontare i problemi della
biologia moderna in strutture di ricerca private e pubbliche. Il dottorato ha
un forte carattere interdisciplinare per cui tutti gli studenti sono esposti a
progetti che traggono vantaggio dall’interazioni con discipline quali la
Chimica le Fisica e soprattutto la Bioinformatica. Possono accedere al
dottorato studenti in possesso di una qualsiasi laurea scientifica che al
momento del colloquio di ammissione mostrino una sufficiente preparazione nelle
discipline biologiche (Attualmente sono iscritti al dottorato studenti in
possesso di una laurea in Biologia, Fisisca e Chimica.
L´attivitá di ricerca, che rappresenta il principale momento formativo del
dottorando, é diretta allo studio, con moderne metodologie molecolari e
cellulari, della biologia delle cellule procariotiche ed eucariotiche a livello
strutturale, metabolico, genetico, di sviluppo, differenziamento. Una
particolare enfasi è riposta nella formazione ad un approccio che sfrutti i
recenti progressi nell’area della genomica e della proteomica. All´attivitá
sperimentale si affianca un´attivitá didattica articolata in progetti formativi
comuni a tutti i dottorandi. Questi progetti possono variare di anno in anno.
Nel corso degli ultimi tre anni i dottorandi hanno costruito una banca dati di
interazioni proteiche (MINT) che è disponibile in rete (http://160.80.34.4/mint)
Questo progetto ha avuto un considerevole visibilità internazionale ed è stato
riconosciuto dall’European Bioinformatic Institute che ha proposto di
sviluppare MINT quale banca dati Europea di interazioni proteiche.
Stages in industrie Biotecnologiche.
Un paio di studenti per anno svolgono la loro attività di ricerca nei
laboratori della Merck Srarp & Dome di Pomezia. Inoltre il dottorato ha
rapporti con la Lay Line Genomics una start up company nell’area sud di Roma
|
1. |
Biologia Molecolare |
|
2. |
Biologia Cellulare, |
|
3. |
Genomica |
|
4. |
Bioinformatica |
|
5. |
Biotecnologie |
|
6. |
Biologia dello sviluppo |
|
7. |
Proteomica |
|
8. |
Virologia |
|
9. |
Microbiologia |
|
10. |
Biochimica |
|
11. |
Genetica |
|
Cognome |
CESARENI |
|
Nome |
Giovanni |
|
Ateneo |
Università degli Studi di ROMA
"Tor Vergata" |
|
Dipartimento |
Dip. BIOLOGIA |
|
Ruolo |
Prof. ordinario |
|
Settore |
BIO/18 |
Partecipanti il collegio (personale di ruolo nelle università italiane)
|
n. |
Cognome |
Nome |
Ateneo |
Dipartimento |
Ruolo |
Settore |
|
1. |
ADUCCI |
Patrizia |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
PO |
BIO/04 |
|
2. |
AMALDI |
Francesco |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
PO |
BIO/11 |
|
3. |
BAGNI |
Claudia |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
PA |
BIO/11 |
|
4. |
BATTISTONI |
Andrea |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
PA |
BIO/10 |
|
5. |
CANINI |
Antonella |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
RU |
BIO/01 |
|
6. |
CANNATA |
Stefano Maria |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
RU |
BIO/06 |
|
7. |
CASTAGNOLI |
Luisa |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
PA |
BIO/18 |
|
8. |
CESARENI |
Giovanni |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
PO |
BIO/18 |
|
9. |
CIRIOLO |
Maria Rosa |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
PO |
BIO/10 |
|
10. |
FALCONI |
Mattia |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
RU |
BIO/11 |
|
11. |
FILONI |
Sergio |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
PO |
BIO/06 |
|
12. |
FREZZA |
Domenico |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
RU |
BIO/18 |
|
13. |
GHIBELLI |
Lina |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
RU |
BIO/13 |
|
14. |
GONFLONI |
Stefania |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
RU |
BIO/18 |
|
15. |
HELMER CITTERICH |
Manuela |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
PA |
BIO/11 |
|
16. |
LO BELLO |
Mario |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
PA |
BIO/10 |
|
17. |
LORENI |
Fabrizio |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
PA |
BIO/11 |
|
18. |
LULY |
Paolo |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
PO |
BIO/09 |
|
19. |
MALASPINA |
Patrizia |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
PA |
BIO/18 |
|
20. |
PAOLOZZI |
Luciano |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
PO |
BIO/18 |
|
21. |
PIACENTINI |
Mauro |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
PO |
BIO/06 |
|
22. |
RAGNINI |
Antonella |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
RU |
BIO/10 |
|
23. |
ROSSI |
Luisa |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
PA |
BIO/10 |
|
24. |
ROTILIO |
Giuseppe |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
PO |
BIO/10 |
|
25. |
RUFINI |
Stefano |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
RU |
BIO/09 |
|
26. |
SANTORO |
Maria Gabriella |
Università degli Studi di ROMA
"Tor Vergata" |
DIP. BIOLOGIA |
PO |
MED/07 |
Personale appartenente ad Università Straniere
|
n. |
Cognome |
Nome |
Struttura |
Dipartimento |
Ruolo |
Settore |
|
1. |
Diederich |
Marc |
Fondation
Recherche sur le Cancer et les Maladies du Sang, Luxemburg |
Laboratoire
de Biologie Moleculaire et Cellulaire du Cancer |
|
|
Partecipanti il collegio (personale non di ruolo nelle università o
dipendente di altri enti)
|
n. |
Cognome |
Nome |
Struttura |
Dipartimento |
Ruolo |
Settore |
|
1. |
Cecconi |
Francesco |
Dulbecco Institute |
|
|
|
Requisiti richiesti per l'ammissione
|
VECCHIO ORDINAMENTO: |
NO |
|
Se non tutte consentono l'accesso, |
Scienze Biologiche,
Biotecnologie, Chimica, Fisica, Informatica |
|
NUOVO ORDINAMENTO: |
NO |
|
Se non tutte consentono l'accesso, |
|
|
Altro per studenti stranieri |
Dichiarazione di Valore; |
|
Altro |
|
|
|
|
|
|
|
|
|
|
|
Attività didattica prevista |
SI |
Non Obbligatorio |
|
-Insegnamenti
previsti nell'iter formativo |
tot CFU 12 |
n.ro insegnamenti 3 |
|
-Insegnamenti
mutuati da corsi di laurea |
SI |
n.ro 3 |
|
Cicli seminariali |
SI |
n.ro 2 |
|
Verifiche annuali previste |
SI |
n.ro 1 |
|
Numero totale delle verifiche |
3 |
|
|
Stage presso |
|
|
|
Soggiorni all'estero |
SI |
Non Obbligatorio |
|
-Periodo
consentito all'estero (in mesi) |
min: 1 |
max: 18 |
|
-Finalità del
soggiorno all'estero |
|
|
Produzione scientifica del collegio dal 1999 al 2004 (personale di ruolo
nelle università italiane)
|
1. |
ADINOLFI S, BAGNI C., MUSCO G.,
MAZZARELLA L, PASTORE A. (1999). Dissecting FMR1, the protein
responsible for fragile X syndrome, in its structural and functional domains.
RNA-A PUBLICATION OF THE RNA SOCIETY. vol. 5, pp.
1248-58. |
|
2. |
ADUCCI P., CAMONI L., MARRA M.,
VISCONTI S., ADUCCI P. (2002). From cytosol to organelles: 14-3-3
proteins as multifunctional regulators of plant cell. IUBMB LIFE. vol. 53, pp. 49-55. |
|
3. |
AKABOSHI S., HOGEMA B.M.,
NOVELLETTO A., MALASPINA P., SALOMONS G. S., MAROPOULOS G.D., JAKOBS C.,
GROMPE M., GIBSON K.M. (2003). Mutational Spectrum of the Succinate
Semialdehyde Dehydrogenase (ALDH5A1) gene and functional analysis of 27 novel
disease-causing mutations in patients with SSADH deficiency. HUMAN MUTATION. vol. 22, pp. 442-450. |
|
4. |
AMICI C., BELARDO G., ROSSI A.,
SANTORO M.G. (2001). ACTIVATION OF IKB KINASE BY HERPES SIMPLEX VIRUS TYPE 1: A NOVEL
TARGET FOR ANTI-HERPETIC THERAPY. JOURNAL OF
BIOLOGICAL CHEMISTRY. vol. 276, pp. 28759-28766. |
|
5. |
AQUILANO K., CIRIOLO M.R. (2003).
Proteasome
activation and nNOS down-regulation in neuroblasom cells expressing a Cu,Zn
superoxide dismutase mutant involved in familial ALS. JOURNAL OF NEUROCHEMISTRY. vol. 85, pp. 1324-1335. |
|
6. |
BAGNI
C., BAGNI C. (2004). Molecular insights into mental retardation: multiple
functions for the Fragile X Mental Retardation Protein?. CURRENT ISSUES IN MOLECULAR BIOLOGY. vol. 6, pp. 57-72. |
|
7. |
BAGNI C., GOGOS JA, BRAY S,
KAFATOS FC, HSU T. (2002). The zinc finger protein CF2 functions downstream of
MEF2 during muscle development in Drosophila. MECHANISMS OF DEVELOPMENT. vol. 117, pp. 265-268. |
|
8. |
BAGNI C., MANNUCCI L., DOTTI
C.G., AMALDI F. (2000). Activity-dependent modulation of dendritic mRNA association to
polysomes. JOURNAL OF NEUROSCIENCE. vol. 20,
RC76, pp. 1-6. |
|
9. |
BAGNI C., MANNUCCI, DOTTI.,
AMALDI. (2000).
Chemical stimulation of synaptosomes modulates a-Ca2+/Calmodulin Protein
Kinase II mRNA Association to Polysomes. JOURNAL NEUROSCIENCE. vol. 20, pp. 1-6. |
|
10. |
BARIL D., MANGANO R., GONFLONI
S., KRETZSCHMAR J., MORO M., BOHMANN D., SUPERTI-FURGA G. (2000). A nuclear tyrosine
phophorylation circuit: c-Jun as an activator and substrate of c-Abl and JKN.
EMBO JOURNAL. vol. 19, pp. 273-281. |
|
11. |
BATTISTONI A, PACELLO F,
FOLCARELLI S, AJELLO M, DONNARUMMA G, GRECO R, AMMENDOLIA MG, ROTILIO G.,
VALENTI P. (2000). Increased expression of periplasmic Cu,Zn superoxide dismutase
enhances the survival of Escherichia coli invasive strains within
nonphagocytic cells. INFECTION AND IMMUNITY.
vol. 68, pp. 30-37. |
|
12. |
BATTISTONI A., PACELLO F.,
FOLCARELLI S., AJELLO M., DONNARUMMA G., GRECO R., AMMENDOLIA M.G., TOUATI
D., ROTILIO G., VALENTI P. (2000). Increased expression of periplasmic
Cu,Zn superoxide dismutase enhances the survival of Escherichia coli invasive
strains within nonphagocytic cells. INFECTION
AND IMMUNITY. vol. 68, pp. 30-37. |
|
13. |
BATTISTONI A., PACELLO F.,
MAZZETTI A.P., CAPO C., KROLL J.S., LANGFORD P., SANSONE A., DONNARUMMA G.,
VALENTI P., ROTILIO G. (2001). A histidine-rich metal binding domain
at the N terminus of Cu,Zn-superoxide dismutases from pathogenic bacteria: a
novel strategy for metal chaperoning. JOURNAL
OF BIOLOGICAL CHEMISTRY. vol. 276, pp. 30315-30325. |
|
14. |
BATTISTONI A., PACELLO F., MAZZETTI
AP, CAPO C, KROLL JS, LANGFORD PR, SANSONE A, VALENTI P, ROTILIO G. (2001). A histidine rich metal binding
domain at the N-terminus of Cu,Zn superoxide dismutases from pathogenic
bacteria. A novel strategy for metal chaperoning. JOURNAL OF BIOLOGICAL CHEMISTRY.
vol. 276, pp. 30315-30325. |
|
15. |
BIALEKWYRZYKOWSKA
U, B.E BAUER, W. WAGNER, S. D. KOHLWEIN, R. J. SCHWEYEN, RAGNINI A. (2000). Low levels of Ypt protein
prenylation cause vesicle polarisation defects and thermosensitive growth
that can be suppressed by genes involved in cell wall maintenance. MOLECULAR MICROBIOLOGY. vol. 35, pp. 1295-1311. |
|
16. |
BLASI P., PILO BOYL P., LEDDA M.,
NOVELLETTO A., GIBSON K.M., JAKOBS C., HOGEMA B., AKABOSHI S., LORENI F.,
MALASPINA P. (2002). Structure of human succinic semialdehyde dehydrogenase gene:
identification of promoter region and alternatively processed isoforms. MOLECULAR GENETICS AND METABOLISM. vol. 765, pp. 348-362. |
|
17. |
BLASI P., PILO BOYL P., LEDDA M.,
NOVELLETTO A., GIBSON KM., JAKOBS C., HOGEMA B., AKABOSHI S, LORENI F.,
MALASPINA P. (2002). Structure of human succinic semialdehyde dehydrogenase gene:
identification of promoter region and alternatively processed isoforms. MOLECULAR GENETICS AND METABOLISM. vol. 76, pp. 348-62. |
|
18. |
BRANNETTI
B., HELMER CITTERICH M. (2003). iSPOT: a web tool to infer the interaction
specificity of families of protein modules. NUCLEIC ACIDS RESEARCH. vol. 31, pp. 3709-3711. |
|
19. |
BRANNETTI B., VIA A., CESTRA G.,
CESARENI G., HELMER CITTERICH M. (2000). SH3-SPOT: an algorithm to predict
preferred ligands of different members of the SH3 gene family. JOURNAL OF MOLECULAR BIOLOGY. vol. 298, pp. 313-328. |
|
20. |
BUI DM, GREGAN J, JAROSCH E,
RAGNINI A., SCHWEYEN RJ. (1999). The bacterial magnesium transporter CorA can
functionally substitute for its putative homologue Mrs2p in the yeast inner
mitochondrial membrane. JOURNAL OF
BIOLOGICAL CHEMISTRY. vol. 274, pp. 20438--20443. |
|
21. |
C. COLUSSI, MC. ALBERTINI, S.
COPPOLA, S. ROVIDATI, F. GALLI, GHIBELLI L. (2000). H2O2-induced block of
glycolysis as an active ADP-ribosylation reaction protecting cells from
apoptosis. FASEB JOURNAL. vol. 14, pp.
2266-2276 ISSN: 0892-6638 Impact Factor: 15.2. |
|
22. |
C.
MICALONI, A.P. MAZZETTI, M. NUCCETELLI, J. ROSSJOHN, W.J. MCKINSTRY, G.
ANTONINI, A.M. CACCURI, A.J. OAKLEY, G. FEDERICI, G. RICCI, M.W. PARKER, LO
BELLO M. (2000). valine 10 may act as a driver for product release from the
active site of human glutathione transferase P1-1. BIOCHEMISTRY. vol. 39, pp. 15961-15970. |
|
23. |
C. MICALONI, K.W. KONG, A.P.
MAZZETTI, M. NUCCETELLI, G. ANTONINI, L. STELLA, W.J. MCKINSTRY, J. ROSSJOHN,
G.FEDERICI, G. RICCI, M.W. PARKER, LO BELLO M. (2003). Engineering a new C-terminal
tail in the H-site of human glutathione transferase P1-1: structural and
functional consequences. JOURNAL OF
MOLECULAR BIOLOGY. vol. 325, pp. 111-122. |
|
24. |
CABIBBO
A., FRANT R.P., HELMER CITTERICH M. (2002). The Internet for Cell and
Molecular Biologists. ISBN: 1-898486-32-8 :
Horizon Scientific Press (UNITED KINGDOM). |
|
25. |
CALDAROLA S., AMALDI F., PROUD
C.G., LORENI F. (2004). Translational regulation of terminal oligopyrimidine mRNA induced by
serum and amino acids involve different signaling events. JOURNAL OF BIOLOGICAL CHEMISTRY. vol. 279, pp. 13522-13531. |
|
26. |
CAMONI L., IORI V., MARRA M.,
ADUCCI P. (2000). Phosphorylation-dependent interaction between plant plasma membrane
H+-ATPase and 14-3-3 proteins. JOURNAL OF
BIOLOGICAL CHEMISTRY. vol. 275, pp. 9919-9923. |
|
27. |
CAMONI L., VISCONTI S.MARRA M.,
MARRA M., ADUCCI P. (2001). Adenosine 5'-Monophosphate inhibits the association
of 14.3.3 proteins with plant plasma membrane H+-ATPase. JOURNAL OF BIOLOGICAL CHEMISTRY. vol. 276, pp. 31709-31712. |
|
28. |
CANINI A., GIOVINAZZI J,
IACOVACCI P, PINI C, GRILLI CAIOLA M. (?). Localization of carbohydrate epitope
recognized by human IgE in pollens of Cupressaceae. JOURNAL OF PLANT RESEARCH. in press. |
|
29. |
CANINI A., LEONARDI D, GRILLI
CAIOLA M. (2001). Superoxide dismutase activity in the cyanobacterium Microcystis
aeruginosa after surface bloom formation. NEW PHYTOLOGIST. vol. 152, pp. 107-116 ISSN: 0028-646X. |
|
30. |
CANINI A., LEONARDI D., RUGGERI
S., CARNOVALE E., GRILLI CAIOLA M. (2001). Intracellular localization of calcium,
phosphorus and nitrogen in common bean seeds (Phaseolus vulgaris L. cv
Borlotto) by SEM, ESI and EELS techniques. PLANT BIOSYSTEMS. vol. 135, pp. 123-321 ISSN: 1126-3504. |
|
31. |
CANINI A., PELLEGRINI S, GRILLI
CAIOLA M. (2003). Ultrastructural variaions in Microcystis aeruginosa (Chroococcales,
Cyanophyta) during a surface bloom induced by high incident light irradiance.
PLANT BIOSYSTEMS. vol. 137, pp. 1-13. |
|
32. |
CANNATA SM, BAGNI C., BERNARDINI
S, CHRISTEN B, FILONI S. (2001). Nerve-independence of limb
regeneration in larval Xenopus laevis is correlated to the level of FGF-2
mRNA expression in limb tissues. DEVELOPMENTAL
BIOLOGY. vol. 231, pp. 436-446. |
|
33. |
CASTEDO M., FERRI K.F., BLANCO
J., ROUMIER T., LAROCHETTE N., BARRETINA J., AMENDOLA A., NARDACCI R.,
METIVIER D., ESTE J.A., PIACENTINI M., KROEMER G. (2001). Human immunodeficiency virus 1
envelope glycoprotein complex-induced apoptosis involves mammalian target of
rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation. JOURNAL OF EXPERIMENTAL MEDICINE. vol. 194 (8), pp. 1097-1110
Impact Factor 15,236. |
|
34. |
CASTEDO M., ROUMIER T., BLANCO
J., FERRI KF., BARRETTINA J., TINTIGNAC LA, ANDREAU A, PERFETTINI JL,
AMENDOLA A, NARDACCI R, LEDUC P., INGBER DE, DRUILLENNEC S, ROQUES B,
LEIBOVITCH SA, VILELLA-BACH M, CHEN J, ESTE JA, MODJTAHEDI N, PIACENTINI M.,
KROEMER G:. (2002).
Sequential Involvement of Cdk1,mTOR and p53 in Apoptosis Induced by the HIV-1
Envelope. EMBO JOURNAL. vol. 21, pp.
4070-4080 I.F. 13.999. |
|
35. |
CIRIOLO M.R., AQUILANO K., DE
MARTINO A., CARRI' M.T., ROTILIO G. (2001). Differential role of superoxide and
glutathione in GSNO-mediated apoptosis.A rationale for mild forms of FALS
associated to less active Cu,Zn superoxide dismutase mutants. JOURNAL OF NEUROCHEMISTRY. vol. 77, pp. 1433-1443. |
|
36. |
CIRIOLO M.R., DE MARTINO,A.,
LAFAVIA,E., ROSSI,L., CARRÌ,M.T., ROTILIO,G. (2000). Cu,Zn-superoxide
dismutase-dependent apoptosis induced by nitric oxide in neuronal cells. JOURNAL OF BIOLOGICAL CHEMISTRY. vol. 275, pp. 5065-5072. |
|
37. |
CIRIOLO MR, AQUILANO K, DE
MARTINO A, CARRI\' MT, ROTILIO G. (2001). Differential role of superoxide and
glutathione in GSNO-mediated apoptosis. A rationale for mild forms of FALS
associated to less active Cu,Zn superoxide dismutase mutants. JOURNAL OF NEUROCHEMISTRY. vol. 77, pp. 1433-1443. |
|
38. |
CIRIOLO MR, DE MARTINO A, LAFAVIA
E, ROSSI L., CARRI\' MT, ROTILIO G. (2000). Cu, Zn superoxide dismutase-dependent
apoptosis induced by nitric oxide in neuronal cells. JOURNAL OF BIOLOGICAL CHEMISTRY. vol. 275, pp. 5065-5072. |
|
39. |
CIRIOLO MR, DEMARTINO A, ROSSI L,
CARRì MT, ROTILIO G. (2000). Cu,Zn superoxide dismutase-dependent apoptosis
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Produzione scientifica del collegio dal 1999 al 2004 (personale non di
ruolo nelle università o dipendenti di altri enti)
Francesco
Cecconi
1. Candé C., Cecconi F., Dessen Ph. and Kroemer G. (2002) Apoptosis inducing
factor (AIF): key to the conserved caspase-independent pathways of cell death?
J. Cell Sci., 115, 4727-4734. 2. Marsden V., O'Connor L., Huang D.C.S.,
Metcalf, D., Cecconi, F., Kuida, K., Tomaselli, K., Silke, J., Vaux, D.L.,
O'Reilly, L.A., Bouillet, P., Adams, J.M. and Strasser, A. (2002) Apoptosis
regulated by Bcl-2 inhibition of caspase activation upstream of Apaf-1 and
caspase-9. Nature, 419, 634-637. 3. Cregan, S.P., Fortin, A., MacLaurin, J.G.,
Callaghan, S.M., Cecconi, F., Park, D.S., Dawson, T.M., Kroemer, G. and Slack,
R.S. (2002) "Apoptosis Inducing Factor Regulates Caspase-independent
neuronal cell death". J. Cell. Biol., 158, 507-517. 4. Matsuki Y., Zhang
H., Hsu H., Yang P., Zhou T., Dodd C., Cecconi F., Gruss P., Tadakuma T. and
Mountz J. (2002) "Different Role of Apaf-1 in Positive Selection, Negative
Selection and Death by Neglect in Foetal Thymic Organ Culture". Scand. J.
Immunol., 56, 174-184. 5. Bitzer M., Armeanu S., Prinz F., Ungerechts G.,
Wybranietz W., Spiegel M., Bernlöhr C., Cecconi F., Gregor M., Neubert W.J.,
Schulze-Osthoff K. and Lauer U.M. (2002) "Caspase-8 and Apaf-1 independent
caspase-9 activation in Sendai virus infected cells". J. Biol. Chem., 277,
29817-29824. 6. O'Reilly, L. A., Harvey, N., Marsden, V., Cullen, L., Vaux,
D.L., Haecker, G., Ekert, P., Magnusson, C., Pakusch, M., Cecconi, F., Kuida,
K., Strasser, A., Kumar, S. and Huang, D.C.S. (2002) "Caspase-2 is not
required for thymocyte or neuronal apoptosis even though cleavage of caspase-2
is mediated by Apaf-1 and caspase-9". Cell Death & Differ., 9,
832-841. 7. Heins, N., Malatesta, P., Cecconi, F., Nakafuku, M., Tucker, K.L.,
Hack, M.A., Chapouton, P., Barde, Y.A., Gotz, M. (2002) "Glial cells
generate neurons: the role of the transcription factor Pax6". Nat.
Neurosci., 5, 308-315. 8. Moreno, S., Ferraro, E., Eckert, S. and Cecconi, F.
(2002) "Apaf1 reduced expression levels generate a mutant phenotype in
adult brain and skeleton". Cell Death
& Differ., 9, 340-342. 9. Cervelli, M., Cecconi, F., Giorgi, M., Annesi, F.
and Mariottini P. (2002) "Comparative structure analysis of vertebrate U17
small nucleolar RNA (snoRNA) ". J. Mol. Evol., 54,166-79. 10. Fortin,
A., Cregan, S.P., MacLaurin, J., Kushwaha, N., Hickman, E.S., Thompson, C.,
Hakim, A., Albert, P.R., Cecconi, F., Helin, K., Park, D.S. and Slack, R.S.
(2001) "APAF1 is a key transcriptional target for p53 in the regulation on
neuronal cell death". J. Cell. Biol.,
155, 207-216.
.