UNIVERSITY OF ROME "TOR VERGATA"	ITALIAN SOCIETY OF BIOCHEMISTRY

Thursday, June 3, 1999

14.00-15.45 Registration

15.45-16.15Welcome to the Participants
 Opening remarks by Alessandro Finazzi Agrò
                                    Rector, University of Rome “Tor Vergata”

16.15-17.00 Opening Lecture
                  Gabriele Varani, MRC Labotatory of Molecular Biology, Cambridge, UK
RNA-binding proteins: structure and recognition from early development to presenile dementia
 

17.00-17.30                       Coffee break
 
 

17.30-18.15 Main lecture
                 Antònio Xavier, Instituto de Tecnologia Quimica e Biologica, Universidade
                     Nova de Lisboa, Oeiras, Portugal
 Structural basis for e^-/H⁺ cooperativity: the redox-Bohr effect

18.15-18.40 Lucia Banci, Dipartimento di Chimica, Università di Firenze
 Structure, dynamics and folding of paramagnetic metalloproteins

18.40-19.05 Maria Antonietta Vanoni, Dipartimento di Fisiologia e Biochimica Generali,
                     Università di Milano
Glutamate synthase: a complex iron-sulfur flavoprotein

19.05-19.30 Alessandro Giuffrè, Centro di Biologia Molecolare del CNR, Dipartimento
                     di Scienze Biochimiche, Università di Roma “La Sapienza”
 On the molecular evolution of NO- and O₂-reductases
 

19.30                                   Welcome buffet

Friday, June 4, 1999

 9.30-10.15 Main Lecture
                Donald W. Nicholson, Dept. Pharmacology, Biochemistry and Molecular
                    Biology, Merck Frosst Centre for Therapeutic Research Montreal, Canada
 Caspase function, regulation and inhibition

10.15-10.40 Edon Melloni, Dipartimento di Medicina Sperimentale, Università di Genova
 Regulation of calcium dependent proteolytic system: new perspectives

10.40-11.10                       Coffee break

11.10-11.35 Paolo Tortora, Dip. di Biotecnologie e Bioscienze, Università Milano-Bicocca
Structural studies on ataxin-3, a protein containing glutamine repeats responsible for a neurodegenerative disease

11.35-12.00 Christian Steinkühler, IRBM  P. Angeletti, Pomezia (RM)
The Hepatitis C virus NS3 protease
 
 

13.30-14.30                            Lunch

15.30-16.15 Main lecture
                  Christian Altenbach, Dept. Chemistry and Biochemistry, UCLA, USA
Structure and structural changes in rhodopsin investigated by site-directed spin
labeling

16.15-16.40 Salvatore Cannistraro, INFM, Università della Tuscia, Viterbo
Solvent-biomolecule dynamics: a neutron scattering-computer simulation
combined approach

16.40-17.10                       Coffee break
 

17.10-17.35 George J. Vella, PerSeptive Biosystems, Framingham, MA, USA
Recent advances in protein analysis: the use of automated multi dimensional chromatography and mass spectrometry for the rapid identification and characterization of proteins

17.35-18.00 Alberto Diaspro, INFM, Sez-B, UdR Genova e Dipartimento di Fisica
                      Università di Genova
Two photon fluorescence microscopy of biological macromolecules

18.00-18.45 Assembly of the Workgroup on the Structure and Function of Proteins

20.00                                       Social dinner

Saturday, June 5, 1999

 9.30-10.15 Main lecture
                Heidi A. Hamm, Northwestern University Institute for Neuroscience, Dep. of
                    Molecular Pharmacology and Biological Chemistry, Chicago, USA
 Structure, function and regulation of heterotrimeric G proteins

10.15-10.40 Lorenzo Pinna, Dipartimento di Chimica Biologica, Università di Padova
 Protein kinase structure-function relationships: a thousand and one variation
 on the teme?

10.40-11.10                       Coffee break
 

11.10-11.35 Giorgio Rispoli, Dipartimento di Biologia, Università di Ferrara
Ca²⁺ transport and Ca²⁺ regulation of phototransduction in rods

11.35-12.00 Daniela Verzili, Centro di Biologia Molecolare del CNR, Dipartimento di
                      Scienze Biochimiche, Università di Roma “La Sapienza”
Ca²⁺-mediated signal transduction by sorcin, a member of the penta EF-hand family. Topology of the interaction with a physiological target, the ryanodine receptor
 
 

12.00-12.30 Remarks by Paolo M. Fasella, Università di Roma “Tor Vergata”
 Proteins at the turn of the millennium: the outline of a book I should like to read

12.30 Closing remarks