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CNR - UNESCO Meeting

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CNR - UNESCO Meeting
1997
CNR - UNESCO AIDS Meeting, Saint Vincent, Valle d'Aosta

AIDS and Tuberculosis: From Immunity to therapy.

Congress Centre, Grand Hotel Billia, Saint Vincent, Valle d'Aosta, November 30 - December 3, 1997

Programma:

REGIONE VALLE D'AOSTA CNR-UNESCO MEETING

AIDS AND TUBERCULOSIS: FROM IMMUNITY TO THERAPY

St. Vincent, Valle d'Aosta, Italy (November 30 - December 3, 1997)

Sunday (November 30)

Therapy and Disease Progression in HIV Infection

L. Montagnier (Paris) - E. Garaci (Rome)

11.30 C.D. Pauza (Madison): Acute viral pathogenesis and AIDS: what sets the set point.
12.00 R. Cauda & L. Ortona (Rome): Activation/costimulatory molecules in HIV disease: their role in the progression of the disease.
12.30 M. L. Gougeon (Paris): Restoration of the immune system under anti-retroviral therapy: analysis of the T cell repertoire, cytokine production and apoptosis.

13.00 Lunch

15.30 M. Andreoni (Rome): Persistent immunological deterioration during protease inhibitor treatment in patients with advanced HIV infection.
16.00 A. Traverso &A. Tassara (Aosta): Clinical aspects of tuberculosis in AIDS-patients.
16.30 A. Berretta (Paris):HIV resistance phenotype conferred by alternative CCR5 gene alterations

17.00 Press Conference: On. Prof. D. Vierin (Presidente Regione Valle d'Aosta)
On. Dr. R. Vicquery (Assessore Regi onale Sanità)
Prof. L. Montagnier (President of the World AIDS fundation, Paris)
Prof. E. Garaci (Presidente Area CNR Tor Vergata, Rome )AA

Cytokines and Macrophages as key Regulators of Immunity

V. Colizzi (Rome) - M. Malkovsky (Madison)

17.40
G.Poli (Milan): Cytokines and HIV: from pathogenesis to treatment.
18.00 M.L.Bocchino (Paris): Single cell analysis of cytokines synthesised by monocytes in HIV infection and tuberculosis.
18.20 C. F. Perno & E. Garaci (Rome): Macrophages and other cells as HIV reservoir: therapeutical applications.
18.40 C.E.Grossi (Genoa): Role of lymph node follicular dendritic cells in HIV-infection
19.00 G. Mancino (Rome): ATP-induced apoptosis of human monocytes/macrophages decreases M. tuberculosis viability: role of purinergic receptors.
20.00 Dinner

Monday (December 1)

New Biotechnological Approaches to Diagnosis and Therapy
A. Cassone (Rome) - J. Ivanyi (London)
9.00 J. Ivanyi (London): DNA vaccination against tuberculosis.
9.20 M. Singh (Braunschweig): Serological diagnosis of tuberculosis.
9.40 Y. Becker (Jerusalem): Development of HIV and M. tuberculosis PEP(DNA)LOTION vaccines for transport to skin Langerhans cells to induce protective cellular immunity.
10.00 F. Mariani (Rome): Identification of differentially expressed M. tuberculosis genes in the course of intra- and extra-cellular growth.
10.20 W.H. Boom (Cleveland): Human T cell subset (CD4+, CD8+, gd) responses to M.tuberculosis.
10.40 M. Malkovsky (Madison): Molecular chaperones in AIDS and cancer therapies.

11.00 Coffee break

11.20 M. S. Salvato (Madison): MHC-unrestricted killing of SIV-env-positive targets.
11.40 F. Titti & P.Verani (Rome): Long lasting protection elicited by immunisation with live attenuated SIV in Cynomologus monkeys.
12.00 J. Heeney (Rijswijk): Cytokines, chemokines and protective immunity to AIDS
12.20 A. Cassone (Rome): Killer toxin mimicking antibodies: an innovative approach to the therapy of opportunistic infections in AIDS.

13.00 Lunch


Satellite Workshop - Monday afternoon (December 1)
European Union Project Copernicus
New Methods for Detection of CD4 T Cell Depletion by Apotosis in AIDS

M.L. Gougeon (Paris)

15.00 M.L. Gougeon (Paris): Apoptosis and AIDS
15.30 M. Piacentini (Rome): Tissue transglutaminase, apoptosis and autoimmunity.
16.00 K..P. Hanson (St.Petersbourg): title to be confirmed.
16.30 L. Fesus (Budapest): title to be confirmed.
17.00 V.Colizzi (Rome): title to be confirmed.
Tuesday (December 2)

Innate Immunity to Infections and the Role for Adaptive Immunity

F. Poccia (Rome) - M.Bonneville (Nantes)

15.00 M. Lopez-Botet (Madrid): The role of CD94/NKG2A receptor in recognition of non classical HLA class I molecules.
15.30 A. Moretta (Genoa): HLA-class I specific inhibitory receptors of NK and T lymphocytes.
16.00 L. Battistini (Rome): Phenotypic and cytokine analysis of human peripheral blood gd T cells expressing NK cell receptors.
16.30 M. Bonville (Nantes): NK receptor mediated control of mayor gd T cell subsets in humans.
17.00 M. Wallace (Madison): gd T lymphocytes in HIV and SIV infection.
17.30 M.L.Gougeon (Paris): gd T cell anergy in HIV infection: influence of cytokines.
18.00 F. Poccia (Rome): in vitro and in vivo T cell response to nonpeptidic antigens.
18.30 F. Dieli & A. Salerno (Palermo): ab and gd T lymphocytes in tuberculosis in childhood.

Social Ski Section at Cervinia - Wednesday (December 3)

Organisers:
V. Colizzi, R. Cauda, M.L. Gougeon, F. Poccia, A. Salerno, P. Vagliani

Secretary:
C. Costa, Department of Biology, University of Rome "Tor Vergata", Tel. ++39 6 7259 4235/7; Fax 72594224;

E-mail: colizzi@utovrm.it - poccia@utovrm.it



The 1997 annual conference is organised by:

the Regione Valle d'Aosta,

the National Research Council,

the UNESCO (Venice Office),

the World Foundation for AIDS Research and Prevention,

the Istituto Superiore di Sanità (ISS-Progetto Nazionale Tubercolosi) and

the European Union Project Copernicus.